Senior Program Manager, AI Programs

Thermo Fisher Scientific · Durham, NC

Posted October 20, 2026

ManagerDataOn site
US$115k to 165k a yearApply

Work Schedule

First Shift (Days)

Environmental Conditions

Office

Job Description

Role purpose

The Senior Program Manager will establish the operating model that brings together AI-related work across platforms, engineering, product, business stakeholders, and vendors.

The role will create a scalable foundation that can eventually support a broader enterprise AI portfolio.

Core responsibilities

  • Establish the program operating model

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  • Facilitate agreement on, document, and maintain governance, decision rights, working forums, intake processes, and escalation paths ,

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  • Create a consistent operating rhythm across participating teams.

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  • Establish a framework that can scale from a single strategic AI platform to a broader portfolio of AI tools and capabilities.
  • Create roadmap and prioritization transparency

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  • Coordinate execution of agreed priorities, cross-team dependencies, and delivery risks.

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  • Partner with product, platform, and engineering leaders to support roadmap alignment and prioritization.

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  • Bring business needs and stakeholder feedback into planning discussions.

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  • Design roadmap practices that can eventually accommodate multiple AI platforms
  • Strengthen business and leadership relations

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  • Build trusted relationships with business stakeholders and represent the AI program clearly.

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  • Improve visibility into what is available, what is planned, and how stakeholders can engage.

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  • Prepare clear updates, roadmaps, showcases, and executive communications.

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  • Serve as a consistent connection point between functional teams, the business, PMO, and senior leadership.
  • Establish metrics and reporting

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  • Define a focused set of standard metrics covering delivery health, adoption, stakeholder satisfaction, risk, and business value.

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  • Establish reporting cadences for working teams, the PMO, and senior leadership.

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  • Create a consistent reporting framework that can expand as additional AI platforms and capabilities are introduced.

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  • Use metrics and feedback to identify improvement opportunities and recommend adjustments.

Success measures

Success will be demonstrated by

  • A clear and consistently used AI program operating model.
  • Visible and aligned roadmaps across product, platform, engineering, and adoption.
  • Stronger business stakeholder relationships and satisfaction.
  • Consistent reporting into the PMO and senior leadership.
  • Improved visibility into risks, dependencies, priorities, and decisions.
  • A scalable framework for incorporating additional AI platforms over time.
  • Clearer evidence of adoption and business value across the AI portfolio.

Soft skills

  • Builds trust across technical, business, and leadership teams.
  • Communicates clearly and simplifies complex topics.
  • Facilitates alignment and influences without direct authority.
  • Creates structure in ambiguous environments.
  • Demonstrates strong judgment, collaboration, and follow-through.
  • Adapts quickly in a changing AI landscape.

Minimum experience

  • 8 years in program management, technical project management, product management, or a related field.
  • Experience leading complex, cross-functional technology initiatives.
  • Experience with AI, enterprise technology, digital transformation, or emerging technologies preferred.

Compensation and Benefits

The salary range estimated for this position based in California is $114,600.00–$165,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs
  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement
  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

Source: Thermo Fisher Scientific's career site. PharmoniQ shows this job as posted and links to the original. Check the employer's page for the latest details.