University of Minnesota Center for Drug Design Pharmacology Core

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Minneapolis, MN · United States

University Core Facilitiessmall

Specialization: Academic ADMET, PK and bioanalysis core

Key Differentiator

Fee-based academic core offering ICH M10 bioanalytical validation alongside in vitro ADMET and rodent PK.

Core Services

LC-MS/MS bioanalysis; In vitro ADMET; Rodent PK; Single and repeat dose toxicity; PK modelling

Capabilities

ICH M10 method validationCYP450 inhibition and phenotypingCaco 2, MDCK and PAMPA permeabilityhERG assaysOral bioavailability in mice and ratsPhoenix WinNonlin PK analysis

Market Intelligence

Part of the Center for Drug Design in the University of Minnesota College of Pharmacy, located in Nils Hasselmo Hall. Works with researchers as grant collaborators or through fee-based services.

Website

drugdesign.umn.edu/pharmacokinetics-laboratory

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